Legal Medicine
Volume 5, Issue 1 , Pages 15-19 , March 2003

The expression of a novel stress protein ‘150-kDa oxygen regulated protein’ in sudden infant death

  • Kazuya Ikematsu

      Affiliations

    • Division of Forensic Pathology and Science, Department of Translational Medical Sciences, Course of Medical and Dental Sciences, Graduate School of Biochemical Sciences, Nagasaki University, Nagasaki City, Nagasaki 852-8523, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-95-849-7076; fax: +81-95-849-7078
    • ,
  • Ryouichi Tsuda

      Affiliations

    • Division of Forensic Pathology and Science, Department of Translational Medical Sciences, Course of Medical and Dental Sciences, Graduate School of Biochemical Sciences, Nagasaki University, Nagasaki City, Nagasaki 852-8523, Japan
    • ,
  • Toshikazu Kondo

      Affiliations

    • Department of Forensic and Social Environmental Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa City, Ishikawa 920-8640, Japan
    • ,
  • Hisayoshi Kondo

      Affiliations

    • Atomic Bomb Disease Institute Division of Scientific Data Registry, Biostatics Section, Nagasaki University School of Medicine, Nagasaki City, Nagasaki 852-8523, Japan
    • ,
  • Kentaro Ozawa

      Affiliations

    • Department of Neuroanatomy, Kanazawa University Faculty of Medicine, 13-1 Takaramachi, Kanazawa City, Ishikawa 920-8640, Japan
    • ,
  • Satoshi Ogawa

      Affiliations

    • Department of Neuroanatomy, Kanazawa University Faculty of Medicine, 13-1 Takaramachi, Kanazawa City, Ishikawa 920-8640, Japan
    • ,
  • Ichiro Nakasono

      Affiliations

    • Division of Forensic Pathology and Science, Department of Translational Medical Sciences, Course of Medical and Dental Sciences, Graduate School of Biochemical Sciences, Nagasaki University, Nagasaki City, Nagasaki 852-8523, Japan

Received 14 May 2002 ,Revised 26 October 2002 ,Accepted 28 October 2002.

References 

  1. Milton JS. Heat shock proteins. J Biol Chem. 1990;265:12111–12114
  2. Heacock CS, Sutherland RM. Induction characteristics of oxygen regulated proteins. Int J Radiat Oncol Biol Phys. 1986;12:1287–1290
  3. Kuwabara K, Matsumoto M, Ikeda J, Hori O, Ogawa S, Maeda Y, et al. Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain. J Biol Chem. 1996;271:5025–5032
  4. Matsushita K, Matsuyama T, Nishimura H, Takaoka T, Kuwabara K, Tsukamoto Y, et al. Marked, sustained expression of a novel 150-kDa oxygen-regulated stress protein, in severely ischemic mouse neurons. Mol Brain Res. 1998;60:98–106
  5. Welti CV, Mittleman RE, Rao VJ. Practical forensic pathology. New York-Tokyo: Igaku Shoin; 1988;
  6. Knight B. 2nd ed.. Forensic pathology. London-Sydney-Auckland: Arnold; 1996;
  7. Naeye RL, Olsson JM, Combs JW. New brain stem and bone marrow abnormalities in victims of sudden infant death syndrome. J Perinatol. 1989;9:180–183
  8. Naeye RL. Brain-stem and adrenal abnormalities in the sudden-infant-death syndrome. Am J Clin Pathol. 1976;66:526–530
  9. Naeye RL. Sudden infant death. Sci Am. 1980;242:56–62
  10. Rognum TO, Saugstad OD. Hypoxantine levels in vitreous humor: evidence of hypoxia in most infants who died of sudden infant death syndrome. Pediatrics. 1991;87:306–310
  11. Aoki Y. Histopathological findings of the lung and trachea in sudden infant death syndrome: review of 105 cases autopsied at Dade County Medical Examiner Department. Jpn J Legal Med. 1994;48:131–139
  12. Takatsu A, Misawa S, Yoshioka N, Nakasono I, Sato Y, Kurihara K, et al. A proposal of essential for forensic pathological diagnosis of sudden infant death syndrome (SIDS). Jpn J Legal Med. 2000;54:247–255
  13. Tamatani M, Matsuyama T, Yamaguchi A, Mitsuda N, Tsukamoto Y, Taniguchi M, et al. ORP-150 protects against hypoxia/ischemia-induced neuronal death. Nat Med. 2001;7:317–323
  14. Takashima S, Becker LE. Delayed dendritic development of catecholaminergic neurons in the ventrolateral medulla of children who died of sudden infant death syndrome. Neuropediatrics. 1991;22:97–99
  15. Takashima S, Mito T, Becker LE. Neuronal development in the medullary reticular formation in sudden infant death syndrome and premature infant. Neuropediatrics. 1985;16:76–79
  16. Yamanouchi H, Takashima S, Becker LE. Correlation of astrogliosis and substance P immunoreactivity in the brainstem of victims of sudden infant death syndrome. Neuropediatrics. 1993;24:200–209

PII: S1344-6223(02)00072-X

Legal Medicine
Volume 5, Issue 1 , Pages 15-19 , March 2003

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