Legal Medicine
Volume 12, Issue 2 , Pages 108-111, March 2010

Genetic analysis of 17 Y-chromosomal STRs haplotypes of Chinese Tibetan ethnic minority group

Division of Molecular Diagnosis, Department of Lab Medicine, West China Hospital, Sichuan University, Chengdu, PR China

Received 22 May 2009; received in revised form 3 November 2009; accepted 6 November 2009. published online 29 January 2010.

Abstract 

We have co-amplified and analyzed 17 Y-chromosomal STRs loci (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, YGATA-H4 and DYS385a/b) in 132 healthy unrelated autochthonous male individuals of Chinese Tibetan ethnic group residing in Lassa area of China. The gene diversity values for the Y-STRs loci ranged from a minimum 0.206 for DYS391 locus to a maximum of 0.912 for DYS385a/b locus in the populations. A total of 123 haplotypes were identified, among which 115 were unique and 8 occurred more than once. The overall haplotype diversity for 17 Y-STRs loci was 0.998. Research results will be valuable for forensic use in the regions and for Chinese population genetic study.

Keywords: Y-chromosomal STRs, Haplotype, Chinese Tibetan ethnic minority group

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PII: S1344-6223(09)00362-9

doi:10.1016/j.legalmed.2009.11.003

Legal Medicine
Volume 12, Issue 2 , Pages 108-111, March 2010

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