Legal Medicine
Volume 12, Issue 2 , Pages 94-96 , March 2010

A silent allele in the locus D19S433 contained within the AmpFℓSTR® Identifiler™ PCR Amplification Kit

  • Akiko Tsuji

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • Corresponding Author InformationCorresponding author.
    • ,
  • Atsushi Ishiko

      Affiliations

    • Forensic Science Laboratory, Fukuoka Prefectural Police Headquarters, Fukuoka 812-8576, Japan
    • ,
  • Takahiro Umehara

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Yosuke Usumoto

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Wakako Hikiji

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Keiko Kudo

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Noriaki Ikeda

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan

Received 5 November 2009 ,Revised 11 December 2009 ,Accepted 11 December 2009.

References 

  1. Tsuji A, Ishiko A, Inoue H, Kudo K, Ikeda N. Analysis of a paternity case in which the alleged father was deceased: single locus mismatch. Fukuoka Acta Med. 2005;96(3):76–80
  2. Mizuno N, Kitayama T, Fujii K, Nakahara H, Yoshida K, Sekiguchi K, et al. A D19S433 primer binding site mutation and the frequency in Japanese of the silent allele it causes. J Forensic Sci. 2008;53(5):1–6
  3. Takayama T, Takada N, Suzuki R, Nagaoka S, Watanabe Y. Identification of a rare mutation in a TH01 primer binding site. Leg Med. 2007;9(6):289–292
  4. Leibelt C, Budowle B, Collins P, Daoudi Y, Moretti T, Nunn G, et al. Identification of a D8S1179 primer binding site mutation and the validation of a primer designed to recover null alleles. Forensic Sci Int. 2003;133:220–227
  5. Ricci U, Melean G, Robino C, Genuardi M. A single mutation in the FGA locus responsible for false homozygosities and discrepancies between commercial kits in an unusual paternity test case. J Forensic Sci. 2007;52(2):393–396
  6. Clayton TM, Hill SM, Denton LA, Watson SK, Urquhart AJ. Primer binding site mutations affecting the typing of STR loci contained within the AmpFℓSTR® SGM Plus™ kit. Forensic Sci Int. 2004;139:255–259
  7. Vanderheyden N, Mai A, Gilissen A, Cassiman JJ, Decorte R. Identification and sequence analysis of discordant phenotypes between AmpFℓSTR® SGM Plus™ and PowerPlex® 16. Int J Legal Med. 2007;121:297–301

PII: S1344-6223(09)00368-X

doi: 10.1016/j.legalmed.2009.12.002

Legal Medicine
Volume 12, Issue 2 , Pages 94-96 , March 2010

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