Y chromosome STR allelic and haplotype diversity in five ethnic Tamil populations from Tamil Nadu, India

Balamurugan, Kuppareddi; Suhasini, G.; Vijaya, M.; Kanthimathi, S.; Mullins, Nicole; Tracey, Martin; Duncan, George

doi:10.1016/j.legalmed.2010.05.008

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Volume 12, Issue 5 , Pages 265-269, September 2010

Y chromosome STR allelic and haplotype diversity in five ethnic Tamil populations from Tamil Nadu, India

Kuppareddi Balamurugan
- School of Criminal Justice, University of Southern Mississippi, 118 College Drive, P.O. Box 5127, Hattiesburg, MS 39406, USA
- Corresponding author. Tel.: +1 601 266 6048; fax: +1 601 266 4391.
G. Suhasini
- Department of Genetics, Postgraduate Institute of Basic Medical Sciences, University of Madras, Chennai 600 113, India
M. Vijaya
- Department of Genetics, Postgraduate Institute of Basic Medical Sciences, University of Madras, Chennai 600 113, India
S. Kanthimathi
- Department of Genetics, Postgraduate Institute of Basic Medical Sciences, University of Madras, Chennai 600 113, India
Nicole Mullins
- School of Criminal Justice, University of Southern Mississippi, 118 College Drive, P.O. Box 5127, Hattiesburg, MS 39406, USA
Martin Tracey
- Department of Biology, Florida International University, University Park Campus, Miami, FL 33199, USA
George Duncan
- DNA Laboratory, Broward County Sheriff’s Office, 201 SE 6th Street, Fort Lauderdale, FL 33301, USA

Received 12 February 2010; received in revised form 10 May 2010; accepted 26 May 2010. published online 12 July 2010.

Abstract

We have analyzed 17 Y chromosomal STR loci in a population sample of 154 unrelated male individuals of the Tamil ethnic group residing in the state of Tamil Nadu, Southern India using AmpFlSTR® Yfiler™ PCR amplification kit. The population samples consist of the following castes: Kongu Gounder (KOG), Nadar Hindu (NAH), Agamudayar (AGA), Parayar (PAR) and other Tamil individuals (MCT) of mixed castes. A total of 152 unique haplotypes were identified among the 154 individuals studied. The haplotype diversity was found to be 0.9935 or higher for all the five groups. The results of population pairwise Fst p values indicate no statistically significant differentiation between the five populations in this study, but the results were highly significant when compared with 12 other global populations (p<0.05). Comparison of populations in this study with other national and global populations using Principal co-ordinate analysis (PCA) using Rst distance matrix indicates a delineation of all the Indian populations from other unrelated populations.