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Legal Medicine provides an international forum for the publication of original articles, reviews and correspondence on subjects that cover practical and theoretical areas of interest relating to the wide range of legal medicine. Subjects covered include forensic pathology, toxicology, odontology, anthropology, criminalistics, immunochemistry, hemogenetics and forensic aspects of biological science with emphasis on DNA analysis and molecular biology. Submissions dealing with medico-legal problems such as malpractice, insurance, child abuse or ethics in medical practice are also acceptable. Letters to the Editor that relate to material published recently in the journal or comment on any aspects of the Journal are welcomed. All submissions are subject to peer review.

Legal Medicine is an international journal sponsored by the Japanese Society of Legal Medicine as its official journal.

1. GENERAL INFORMATION

Submission to Legal Medicine proceeds online via Elsevier Editorial System - External link http://ees.elsevier.com/legmed. Authors will be guided step-by-step through uploading files directly from their computers. Electronic PDF proofs will be automatically generated from uploaded files, and used for subsequent reviewing.

Authors should send queries concerning the submission process or journal procedures to AuthorSupport@elsevier.com. Authors can check the status of their manuscript within the review procedure using Elsevier Editorial System.

Authors submitting hard copy papers will be asked to resubmit using Elsevier Editorial System.

Submission of an article is understood to imply that the article is original and is not being considered for publication elsewhere; multiple submissions is not acceptable to the Editor, and any such papers, together with future submissions from the authors, will be rejected outright. Submission also implies that all Authors have approved the paper for release and are in agreement with its content.

Upon acceptance of an article, Authors will be asked to transfer copyright (for more information on copyright see External link http://www.elsevier.com/authors). This transfer will ensure the widest possible dissemination of information. A letter will be sent to the corresponding Author confirming receipt of the manuscript. A form facilitating transfer of copyright will be provided.

All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content, (3) final approval of the version to be submitted.

Acknowledgements
All contributors who do not meet the criteria for authorship as defined above should be listed in an acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, writing assistance, or a department chair who provided only general support. Authors should disclose whether they had any writing assistance and identify the entity that paid for this assistance.

Conflict of interest
At the end of the text, under a subheading "Conflict of interest statement" all authors must disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding.

Role of the funding source
All sources of funding should be declared as an acknowledgement at the end of the text. Authors should declare the role of study sponsors, if any, in the study design, in the collection, analysis and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication. If the study sponsors had no such involvement, the authors should so state.

The Journal publishes original material in the following categories:

Original Article (full-paper): full-length research report.

Brief Communication: description of a technical aspect of a field or issue, report on a procedure or method, or work on validation of techniques or methods. Usually a brief description or analysis of an unusual case or a small series of cases. Case reports are acceptable only if the contribution to the better understanding in forensic pathology, forensic toxicology, or medical law is clearly described.

Review: full-length paper reviewing the state of the art or the published literature in a particular area of general interest to the readership.

Announcement of population data: Authors are invited to submit population data to the journal in table format: as an example, please refer to Legal Medicine volume 5 (2003), pages 112-113.

Letter to the Editor: usually a discussion of a previously published item or commentary on the Journal. Publication of letters is solely at the discretion of the Editor. Letters commenting on previously published items are ordinarily shared with the original authors to afford them an opportunity to respond to the commentary.

Papers submitted are subject to peer review. Papers will be evaluated by at least two anonymous persons, either members of the Editorial Board or qualified invited referees. Authors may expect to hear a decision -- acceptance, revision, or rejection -- from the Editor-in-Chief within 6 to 8 weeks after the paper has been received. Papers requiring revision and/or shortening will be returned to the authors by the Editor-in-Chief specifying the requested alterations and including the (anonymous) referee reports. Authors are requested to submit the revised paper within 3 months to the Editor-in-Chief; if submitted at a later date, it will be treated as a new paper and the date of receipt will be altered to the date of submission of the revised paper.

Manuscripts should be written in clear and grammatical English and should conform to the general style of the journal and the specific instructions listed below. Manuscripts that are not properly prepared will be returned to the authors without review, since it is not feasible for the Editors to undertake extensive revision or rewriting of manuscripts submitted.

External link Http://www.elsevier.com/authors provides both the new and seasoned journal author with helpful information, services and tools about submission, support, and efficient and timely production and distribution. External link Http://www.elsevier.com/languagepolishing provides details of some companies who can provide English language and copyediting services to authors who need assistance before they submit their article or before it is accepted for publication. Authors should contact these services directly.

Please note that Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside vendors through our services or in any advertising. For more information please refer to our terms & conditions External link http://authors.elsevier.com/termsandconditions.

Papers should be concise, but with sufficient experimental detail to permit a critical appraisal of the work. Unnecessary repetition should be avoided. Responsibility for the accuracy of materials in the manuscripts, including appropriate references to related work, lies entirely with the authors.

Ethics

The authors should keep in mind possible ethical issues involved in their manuscripts (text and photographs).

Where relevant, manuscripts submitted for publication must contain a statement (e.g. in the Materials and Methods section) to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in Declaration of Helsinki of 1975, and revised in 1983. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.

Reports of animal experiments must state that the investigation conforms with the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health (NIH Publication No. 85-23, revised 1996), or with any specified national law on the care and use of laboratory animals.

2. FORM AND STYLE OF MANUSCRIPT

Manuscripts should conform to the style and usage of the Journal as exemplified in current issues. They should be typed with double-spacing throughout and wide margins (at least 2.5cm). Separate sheets should be started for each of the following: (1) title page, (2) abstract and keywords, (3) text, (4) references, (5) table(s), (6) legend(s) to figure(s), (7) figures or other supplementary material. Manuscripts should be arranged in the order indicated above and all sheets, except the figure(s), should be numbered consecutively with the title page being page 1. Indicate the appropriate location in the text of the tables, figures, and other supplementary material by encircled marginal notes. Latin words or abbreviations, such as in vitro, i.e., per se, should not be italicised. Footnote(s) to the title, author's name(s), and affiliation(s) should appear on the title page. Footnotes in the main text should be numbered consecutively with superscript Arabic numerals, starting with the title page footnote(s). Footnotes to tables should be identified with superscript lower case (a, b, etc.), and placed at the bottom of the table.

3. ORGANIZATION OF MANUSCRIPT

Original Articles and Brief Communications should be organized as follows: Abstract and Keywords, Introduction, Materials and Methods, Results, Discussion, Acknowledgements, References, Tables, Legends to Figures, Figures. Sections should be numbered from the Introduction onward, e.g. 1. Introduction, 2. Materials and Methods etc. In some cases, presentation will be more clear and effective if the author combines some of these sections, such as Results and Discussion.

3.1. Title Page(s)
Provide a title page(s) containing the following items:
(1) The form of the paper (Original Article, Brief Communication, and so on)
(2) Title. The title should be informative and as short as is consistent with clarity. The title should not include chemical formulae or arbitrary abbreviations. The numbering of parts in a series of papers is not permitted, but titles and subtitles may be used if necessary.
(3) Authors' names and affiliations. All authors' names should follow the title, with the first or middle names written out in full, as illustrated below. The name(s) of the department(s) where the work was carried out should be given below the authors names. If the work was carried out at more than one department, this should be indicated as follows:

Detection of the two short tandem repeat loci (HumTPO and HumLPL) in Japanese populations using discontinuous polyacrylamide gel electrophoresis

Haruo Takeshitaa, Toshihiro Yasudaa, Reiko Iidab, and Koichiro Kishia
aDepartment of Legal Medicine, Gunma University School of Medicine, Gunma 371-8511, Japan
bDepartment of Legal Medicine, Fukui Medical School, Fukui 910-1193, Japan


If the address of the author has changed before the expected date of publication, a new address should be given on the title page.
(4) Corresponding Author's address. The name, complete mailing address, telephone number, fax number and e-mail address of the person to whom correspondence and proofs should be sent should be provided. In view of efficiency of handling proofs, the Publisher will send proofs by e-mail in PDF format, together with instructions. Authors who cannot handle proofs by e-mail should indicate this on the title page.
(5) Abbreviations. Non-standard abbreviations should be defined the first time they occur, even if they are known to those familiar with the field.

3.2. Abstract and key words
Every paper should have an abstract and key words.

(1) The second page of the manuscript should be reserved for the Abstract. The Abstract should concisely and clearly describe the major findings reported in the manuscript. It must not exceed 200 words. The Abstract should be intelligible to the non-specialist in the field, and hence should avoid specialized terms and abbreviations or symbols that require definition. It should be understandable in itself, without reference to the main body of the text, since it will frequently be used independently. If it is essential to cite a reference, then complete publication data must be provided.

(2) Authors are requested to provide a maximum of six key words following the Abstract. They should cover the content of the submitted paper precisely and should give readers sufficient information as to the relevance of the paper to their particular field.

3.3. Introduction
The Introduction should present the purpose of the studies reported and their relationship to earlier work in the field. It should not be an extensive review of the literature and should not, in general, exceed two typed pages.

3.4. Materials and Methods
The Materials and Methods section should be as brief as possible, but sufficiently descriptive to permit a qualified reader to repeat the experiments reported. Only truly new procedures should be described in detail; previously published procedures should be cited as references. Modifications of previously published procedures need be given in detail only when this is necessary to repeat the work. In a case report, the case history should be presented in this section. Describe statistical methods in sufficient detail to enable a knowledgeable reader with access to the original data to verify the reported results. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as confidence intervals).

3.5. Results
The Results of experiments should be presented in figures and tables, although some results that do not require documentation may be given solely in the text. Discussion in this section should not be extensive.

3.6. Discussion
The Discussion should be concise (usually less than four typed pages) and should focus on the interpretation of the results, rather than a repetition of the Results section. In some shorter papers, combining the Results and Discussion into one section entitled Results and Discussion may provide a clearer presentation.

3.7. Acknowledgments
Acknowledgments should be presented at the end of the main text, in a separate section. One or more statements should specify (a) contributors that need acknowledgment but do not justify authorship, such as general support by a department chair; (b) acknowledgments of technical help and cooperation; (c) acknowledgments of financial and material support, specifying the nature of the support.

3.8. References
References should be cited in the text, tables, and legends by Arabic numerals in square brackets and listed at the end of the paper in numerical order, typed double-spaced on a separate sheet, under the heading References. The titles of journals should be abbreviated according to the style used in Index Medicus. References to "unpublished experiments" and "personal communications" should appear parenthetically in the text following the name(s) of the source of information [(Yamada T, personal communication), (Suzuki M and Yoshida M, unpublished observations) etc.]. Be sure to verify the wording of any personal communication with the person who supplied the information and obtain approval for the use of his or her name in connection with the quoted information.
Please note the following examples according to the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (New Engl J Med 1997; 336: 309-315).

(1) For a journal article:
[7] Ishida K, Zhu BL, Maeda H. A quantitative RT-PCR assay of surfactant-associated protein A1 and A2 mRNA transcripts as a diagnostic tool for acute asphyxial death. Legal Med 2002; 1: 7-12.

(2) For a chapter in an edited book:
[12] Eisenmenger W, Gilg T. Asphyxia. In: Payne-James J, Busuttil A, Smock W, editors. Forensic Medicine: Clinical and Pathological Aspects; First publication, London: Greenwich Medical Media, 2003, pp. 259-273.

(3) For a book by one or more authors:
[15] Rudin N, Inman K. An introduction to forensic DNA analysis. Boca Raton: CRC Press, 2002. pp.139-156.

Articles or books written by more than two authors should be cited in the text as follows: Smith et al. In the reference list, however, the names of all authors (with initials) must be given. If an article has been accepted for publication by a journal but has not yet appeared in print, the reference should be styled as follows:
[29]. Tanahashi H, Ito T. Molecular characterization of a novel factor recognizing the interleukin-6 responsive element. J Biochem (in press).
The use of "in preparation" or "submitted for publication" is not permitted in the reference list, but may be included in the text. Citation of the references written in a language which is usually unreadable for general readers, and those published in a journal (or book) which general readers cannot easily access, should be avoided.

4. PREPARATION OF TABLES

Only essential data or data needed to illustrate or prove a point should be included as Tables.
(1) Tables should be prepared on separate sheets, numbered consecutively with Arabic numerals according to their sequence in the text, and collected at the end of the manuscript.
(2) Each Table should have above it an explanatory title and sufficient experimental detail, usually in a paragraph immediately following the title, to be intelligible without reference to the text.
(3) Indicate units of measurement clearly.
(4) Footnotes to Tables should be kept to a minimum and should be indicated by superscript lower-case letters at the bottom of the Table.

5. PREPARATION OF ILLUSTRATIONS

• The number of figures used to present data essential to illustrate or prove a point should be kept to a minimum
• Reference should be made in the text to each illustration. Figures will be reduced to fit to the size of one column (7.5 cm) or two columns (16 cm), and any lettering should be large enough to allow this reduction without becoming illegible
• Each figure should be accompanied by a title and an explanatory legend on a separate page called Legends to Figures. There should be sufficient experimental details in the legend to make the figure intelligible without reference to the text
• Legends to Figures should be typed double-spaced, in numerical order, on a separate page
• Photographs should be as high in contrast as possible
• Indicate the magnification of photomicrographs in bar scales on the illustration itself instead of numerical magnification factors
• Make sure you use uniform lettering and sizing of your original artwork
• Save text in illustrations as "graphics" or enclose the font
• Only use the following fonts in your illustrations: Arial, Courier, Helvetica, Times, Symbol
• Number the illustrations according to their sequence in the text
• Use a logical naming convention for your artwork files
• Provide all illustrations as separate files and as hardcopy printouts on separate sheets
• Provide captions to illustrations separately
• Produce images near to the desired size of the printed version

A detailed guide on electronic artwork is available on our website: External link http://www.elsevier.com/artworkinstructions
You are urged to visit this site; some excerpts from the detailed information are given here.

Formats
Regardless of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats (Note the resolution requirements for line drawings, halftones, and line/halftone combinations given below.):
EPS: Vector drawings. Embed the font or save the text as "graphics".
TIFF: Colour or greyscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (colour or greyscale): a minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications please supply "as is".

Please do not:
• Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low
• Supply files that are too low in resolution
• Submit graphics that are disproportionately large for the content

If, together with your accepted article, you submit usable colour figures, Elsevier will ensure that these figures will appear in colour completely free-of-charge in the electronic version of your paper, regardless of whether or not these illustrations are reproduced in colour in the printed version. Colour illustrations can only be included in print if the additional cost of reproduction (EUR 272 for the first page, and EUR 182 for the second and subsequent pages) is contributed by the author: you will receive information regarding the costs from Elsevier after receipt of your accepted article. Please note that because of technical complications which may arise by converting colour figures to 'grey scale' (for the printed version, should you not opt for colour in print), you should submit in addition usable black and white prints corresponding to all the colour illustrations.

6. PREPARATION OF SUPPLEMENTARY DATA

Supplementary files supplied will be published online at no cost alongside the electronic version of your article. Supplementary files include, but are not limited to, supporting applications, movies, animation sequences, high-resolution images, background datasets, and sound clips. Please ensure that data are provided in one of our recommended file formats to ensure that your submitted material is directly usable. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For further information on the preparation of electronic artwork, please see External link http://www.elsevier.com/artworkinstructions.

7. COPYRIGHT

If excerpts from other copyrighted works are included, the Author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by Authors in these cases: contact Elsevier's Rights Department, Oxford, UK: phone (+1) 215 239 3804 or +44(0)1865 843830, fax +44(0)1865 853333, e-mail healthpermissions@elsevier.com. Requests may also be completed online via the Elsevier homepage (External link http://www.elsevier.com/locate/permissions ).

Material in unpublished letters and manuscripts is also protected and must not be published unless permission has been obtained.

8. AUTHORS RIGHTS

As an author you (or your employer or institution) may do the following:
• make copies (print or electronic) of the article for your own personal use, including for your own classroom teaching use
• make copies and distribute such copies (including through e-mail) of the article to research colleagues, for the personal use by such colleagues (but not commercially or systematically, e.g., via an e-mail list or list server)
• post a pre-print version of the article on Internet websites including electronic pre-print servers, and to retain indefinitely such version on such servers or sites
• post a revised personal version of the final text of the article (to reflect changes made in the peer review and editing process) on your personal or institutional website or server, with a link to the journal homepage (on elsevier.com)
• present the article at a meeting or conference and to distribute copies of the article to the delegates attending such a meeting
• for your employer, if the article is a 'work for hire', made within the scope of your employment, your employer may use all or part of the information in the article for other intra-company use (e.g., training)
• retain patent and trademark rights and rights to any processes or procedure described in the article
• include the article in full or in part in a thesis or dissertation (provided that this is not to be published commercially)
• use the article or any part thereof in a printed compilation of your works, such as collected writings or lecture notes (subsequent to publication of your article in the journal)
• prepare other derivative works, to extend the article into book-length form, or to otherwise re-use portions or excerpts in other works, with full acknowledgement of its original publication in the journal

9. FUNDING BODY AGREEMENTS AND POLICIES

Elsevier has established agreements and developed policies to allow authors who publish in Elsevier journals to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit External link http://www.elsevier.com/fundingbodies

10. PROOFS AND OFFPRINTS

Proofs will be sent to the corresponding author together with the offeprint order form. If an e-mail address is supplied, proofs will be sent as e-mail attachment in PDF format, together with instructions. Authors are requested to return corrections by e-mail or fax within 48 hours. Authors will be charged for extensive alterations in the proofs. Fifty free offprints of each article will be supplied. Additional offprints can be ordered at the price shown on the offprint order form.

Legal Medicine does not have page charges.